The main aim of this work is to develop and characterise biocomposites for tissue engineering applications. The biocomposites are made of a polyurethane polymer and a hydroxyapatite. By combining a polymer and a ceramic material can be formed biocomposites for bone tissue engineering applications, since the structure of bone can be grossly described as a collagen-hydroxyapatite composite. Structural properties and degradation rates in vitro of the composites were determined. The in vitro biodegradation of the composite in the phosphate buffered saline solution increased with incubation time and the rate differed with the coating concentration. The results demonstrate that the scaffold with low hydroxyapatite content will have higher degradation rate than that with high hydroxyapatite content.